Pick-Ups

Tarot Cards
{| class="wikitable" Item Icon Item Name Effect
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XXII 

The Bargain Used in a shop causes all items to become half off. Used in a devil room cause all items to become 1 heart.
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XXIII 

Wisdom Spawns a fortune teller machine.
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XXIV 

The Scribe When used gives a random book effect.
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XXV 

Disease Poisons all enemies in a room.
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XXVI 

The Angel Make Light Beams fall off the Sky. A one-use version of "Crack in The Sky" item XXVII 
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The Servant Gives Isaac a random familliar for the room. A one-use "Monster Manuel" item. XXVIII 
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The Gates Unlocks all locked doors on the floor.
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XXIX Descendance

Spawns a trapdoor similar to "We need to go deeper." Lets Isaac skip to the next floor. <p style="text-align: center;">XXX 
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<p style="text-align: center;">Cutlery Gives Isaac Mom's Knife for the room. <p style="text-align: center;">XXXI 
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<p style="text-align: center;">Plague Gives Isaac five attack flies.
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<p style="text-align: center;">XXXII 

<p style="text-align: center;">Repentance Removes one of the players items and restarts the floor. A worse version of "Forget Me Now". By Qrsyua <p style="text-align: center;">XXXIII 
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<p style="text-align: center;">Worship Rare. If devil room spawns/will spawn on floor it makes it a 50/50 chance that either the items in the devil room will cost 1 heart or free, or the room will be an angel room with 2 items. By Qrsyua
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<p style="text-align: center;">XXXIV 

<p style="text-align: center;">Eternity Grants an "Eternal Heart". By Qrsyua
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<p style="text-align: center;">XXXV 

<p style="text-align: center;">Corruption Rare. Brings player to I am Error room. By Qrsyua
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<p style="text-align: center;">XXXVI 

<p style="text-align: center;">Reconcile Rare. Brings player to next major boss (ie. Mom, Moms Heart, It lives, Isaac, Satan, Blue Baby). By Qrsyua
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<p style="text-align: center;">XXXVII 

<p style="text-align: center;">Ras Jaune Fill room w/ urine. Does damage to everything and destroys rocks.
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<p style="text-align: center;">XXXVIII 

<p style="text-align: center;">The Imp Spawns a Demon Beggar. <p style="text-align: center;">XXXIX 
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<p style="text-align: center;">Immolation Teleports user to Sacrifice/Curse Room. By Qrsyua
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<p style="text-align: center;">XL 

<p style="text-align: center;">Power Re-charges your item. By BloodthirstyCZ
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<p style="text-align: center;">XLI 

<p style="text-align: center;">The Treasure Turns all normal chests into golden chests in your level. By BloodthirstyCZ <p style="text-align: center;">XLII 
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<p style="text-align: center;">Hellfire Gives player Brimstone for a room. <p style="text-align: center;">XLIII 
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<p style="text-align: center;">The Heavenlight Gives player The Wafer and the Holy Grail effect for a room.
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<p style="text-align: center;">XLIV 

<p style="text-align: center;">Seige Maxes players attack stat for the floor. By Qrsyua
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<p style="text-align: center;">XLV 

<p style="text-align: center;">Momentum Maxes players speed stat for the floor. By Qrsyua
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<p style="text-align: center;">XLVI

<p style="text-align: center;">Barrage Maxes players tears stat for the floor. By Qrsyua
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<p style="text-align: center;">XLVII Surge Maxes shot speed stat for a floor. By Qrsyua
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<p style="text-align: center;">XLVII 

<p style="text-align: center;">Dimension Maxes range stat for a floor. By Qrsyua <p style="text-align: center;">XLVIII 
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<p style="text-align: center;">Coincidencion Random tarot card effect. By BloodthirstyCZ
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<p style="font-size: 13px; text-align: center;">XXXXX 

<p style="font-size: 13px; text-align: center;">Revenge

Brings the player to the boss room of "The Chest" By dragonspiral123
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<p style="text-align: center;">'''??? '''

<p style="text-align: center;">The Firebird Deals damage to all bosses and enemies in the room, reveals the whole room, maxes out your stats, gives 5 second invincibility, and gives you flaming tears for the rest of the room. ''Comment on Firebird: So... pretty much an even more broken "The Sun"?''
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<p style="text-align: center;">'''??? '''

<p style="text-align: center;">The Cold Freezes all enemies and moving bosses for 5 seconds, similar to Mom's Bra.
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Playing Cards
<p style="text-align: center;">King of Hearts A rarer version of Two of Hearts. Heals Isaac to full health.
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<p style="text-align: center;">Queen of Spades A rarer version of Two of Spades. Gives Isaac a golden key.
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<p style="text-align: center;">Jack of Diamonds A rarer version of Two of Diamonds. Gives Isaac the Quarter. All pennies where the card was used will become nickels/dimes.
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<p style="text-align: center;">Ace of Clubs Drops 1 or 11 bombs, depending on players luck (Lucky Toe/Foot ; Luck Up/Down pills)
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<p style="text-align: center;">10 of Clubs

<p style="font-size:13px;">Drops 10 troll bombs and 5 normal bombs randomly in the room. Grants Isaac a brief force field until the troll bombs detonate.
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Passtivateds
Passtivateds are items that give you a passive effect, but also can have an triggerabel skill. You can only have one at a time but they have their own slots, much like pills and trinkets. "The Pony" and "White Pony" are passtivateds.